CJC-1295 + DAC 5mg

$ 52

Out of stock

CJC-1295 with DAC is a synthetic 30-amino acid analog of Growth Hormone-Releasing Hormone (GHRH). By incorporating the Drug Affinity Complex (DAC), this peptide covalently binds to circulating albumin, extending its research half-life from minutes to several days. It is a premier tool for investigating sustained endogenous growth hormone (GH) elevation and hepatic IGF-1 production without the need for frequent administration.

Description

Sustained Endocrine Signaling for Advanced Metabolic Research

CJC-1295 with DAC represents a major breakthrough in pharmacokinetic engineering. While standard GHRH analogs (like Sermorelin or CJC-1295 No DAC) are rapidly degraded by enzymes, the addition of the Drug Affinity Complex (DAC) allows the peptide to hitchhike on albumin in the bloodstream. This protects the peptide from peptidase degradation and renal clearance, providing a consistent "bleed" of GH stimulation rather than a short-lived spike.

In laboratory settings, CJC-1295 with DAC is primarily used to study the long-term effects of elevated basal growth hormone levels.

The "DAC" Advantage in Research

The inclusion of DAC (Drug Affinity Complex) transforms the peptide’s utility in a lab environment:

  • Extended Bioavailability: Research indicates that a single administration can keep GH and IGF-1 levels elevated for up to two weeks.

  • Preserved Pulsatility: Unlike synthetic HGH, which can shut down natural production, research suggests that CJC-1295 with DAC allows the pituitary gland to maintain its natural pulsatile release pattern, albeit at a significantly higher baseline (trough) level.

  • Efficiency: Ideal for long-term studies where minimal handling of research subjects is required.

Mechanism of Action

CJC-1295 with DAC acts as a selective agonist of the GHRH receptors in the anterior pituitary. Once bound, it triggers the synthesis and release of endogenous growth hormone. This GH then signals the liver to produce Insulin-like Growth Factor 1 (IGF-1), the primary mediator of the peptide's anabolic and regenerative observations.

 

Technical Specifications

Feature Details
Product Name CJC-1295 with DAC
Synonyms DAC:GRF, Drug Affinity Complex: Growth Hormone Releasing Factor
CAS Number 863288-34-0
Sequence Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Lys(Mal)-NH2
Purity ≥ 99.0% (Verified by HPLC/MS)
Storage Store at -20°C (Lyophilized). Stable at room temp for 3 weeks during transit.

Key Research Applications

  • Metabolic Research: Investigating the role of sustained GH elevation on adipose tissue lipolysis and glucose metabolism.

  • Tissue Repair & Recovery: Studying the rate of protein synthesis and collagen cross-linking in musculoskeletal injury models.

  • Anti-Aging & Senescence: Exploring the correlation between youthful IGF-1 levels and markers of cellular aging.

  • Deep Sleep Studies: Analyzing the impact of GHRH analogs on slow-wave sleep patterns and nocturnal recovery.


⚠️ Important Safety & Legal Disclaimer

FOR RESEARCH USE ONLY. NOT FOR HUMAN CONSUMPTION.

This product is sold by Pepformance.com explicitly for laboratory research, analysis, and scientific study.

  • Not for human use: This product is not FDA-approved and is not intended to treat, cure, or prevent any disease or medical condition.

  • Compliance: Any mention of clinical usage, personal dosing, or human application will result in a permanent ban and order cancellation.

  • Handling: Must be handled by trained professionals in a controlled laboratory environment.

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